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Tue, Jun 18, 2019

The Health Benefits of Fruits and Vegetables

1. American Cancer Society Inc. 2001. www.cancer/org. Surveillance Research, accessed 01/29/02.
2. World Cancer Research Fund (American Institute for Cancer Research). Food Nutrition and the Prevention of Cancer: a Global Perspective. 1997.
3. Terry P, Terry JB, Wolk A. Fruit and vegetable consumption in the prevention of cancer: an update. J Int Med. 2001;250:280-290.
4. Feskanich D, Ziegler RG, Michaud DS, et al. Prospective study of fruit and vegetable consumption and risk of lung cancer among men and women. J Natl Cancer Inst. 2000;92(22):1812-1823.
5. Voorips LE, Goldbohm RA, Verhoeven DT, van Poppel G, Sturmans F, Hermus RJJ. Vegetable and fruit consumption and lung cancer risk in the Netherlands Cohort Study on diet and cancer. Cancer Causes and Control. 2000;11:101-115.
6. Michaud DS, Feskanich D, Rimm EB, et al. Intake of specific carotenoids and risk of lung cancer in two prospective U.S. cohorts. Am JClin Nutr. 2000;72:900-997.
7. Marchand LL, Murphy SP, Hankin JH, Wilkens LR, Kolonel LN. Intake of flavonoids and lung cancer. J Natl Cancer Inst. 2000;92:154-160.
8. Jansen MC, Bueno-de-Mesquita HB, Rasanen L, et al. Cohort analysis of fruit and vegetable consumption and lung cancer mortality in European men. Int J Cancer. 2001;92:913-918.
9. Smith-Warner SA, Spiegelman D, Yaun S-S, et al. Intake of fruits and vegetables and risk of breast cancer. JAMA. 2001;285:769-776.
10. Terry P, Wolk A, Magnusson C. Brassica vegetables and breast cancer risk. JAMA. 2001.
11. Fowke JH, Longcope C, Hebert JR. Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women. Cancer Epidem, Bio & Prev. 2000;9:773-779.
12. Cohen JH, Kristal AR, Stanford JL. Fruit and vegetable intakes and prostate cancer risk. J Natl Cancer Inst. 2000;92:61-68.
13. Steinmetz KA, Potter JD. Vegetables, fruit and cancer prevention: A review. JADA. 1996;96:1027-1093.
14. Terry P, Giovannucci E, Michels KB, et al. Fruit, vegetables, dietary fiber, and risk of colorectal cancer. J Natl Cancer Inst. 2001;93:525-533.
15. Michels KB, Giovannucci E, Joshipura KJ, et al. Prospective study of fruit and vegetable consumption and incidence of colon and rectal cancers. J Natl Cancer Inst. 2000;92:1740-1752.
16. Voorips LE, Goldbohm RA, van Poppel G, Sturmans F, Hermus RJJ, van den Brandt PA. Vegetable and fruit consumption and risks of colon and rectal cancer in a prospective cohort study. Am J Epidemiol.2000;152:1081-1092.
17. Flood A, Schatzkin A. Colorectal cancer: Does it matter if you eat your fruits and vegetables. J Natl Cancer Inst. 2000;92(21):1706-1707.
18. Zhang SM, Hunter DJ, Rosner BA, et al. Intakes of fruits, vegetables, and related nutrients and the risk of Non-Hodgkins Lymphoma among women. Cancer Epidem, Bio & Prev. 2000;9:477-485.
19. McCann SE, Moysich KB, Mettlin C. Intakes of selected nutrients and food groups and risk of ovarian cancer. Nutr and Cancer.2001;39(1):19-28.
20. Cramer DW, Kuper H, Harlow BL, Titus-Ernstoff L. Carotenoids, antioxidants and ovarian cancer risk in pre-and post-menopausal women. Int J Cancer. 2001;94:128-134.
21. Gallus S, Bosetti C, Franceschi S, et al. O esophageal cancer in women: tobacco, alcohol, nutritional and hormonal factors. Brit J Cancer. 2001;85(3):341-345.
22. Castellsague X, Munoz N, De Stefani E, Victoria CG, Castelletto R, Rolon PA. Influence of mate drinking, hot beverages and diet one sophageal cancer risk in South America. Int J Cancer. 2000;88:658-664.
23. De Stefani E, Brennan P, Boffetta P, Ronco AL, Mendilaharsu M, Deneo-Pellegrini H. Vegetables, fruits, related dietary antioxidants, and risk of squamous cell carcinoma of the esophagus: A case control study in Uruguay. Nutr and Cancer. 2000;38(1):23-29.
24. Bosetti C, Vecchia CL, Talamini R, et al. Food groups and risk of squamous cell esophageal cancer in northern Italy. Int J Cancer.2000;87:289-294.
25. De Stefani E, Boffetta P, Oreggia F, et al. Plant foods and risk of laryngeal cancer: A case-control study in Uruguay. Int J Cancer.2000;87:129-132.
26. Nagano J, Kono S, Preston DL, et al. Bladder-cancer incidence in relation to vegetable and fruit consumption: A prospective study of atomic-bomb survivors. Int J Cancer. 2000;86:132-138.
27. Steinmaus CM, Nunex S, Smith A. Diet and bladder cancer: a meta analysis of six dietary variables. Am J Epidemiol. 2000;151:693-702.
28. Michaud DS, Spiegelman D, Clinton S, Rimm EB, Willett WC, Giovannucci E. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst. 1999;91:605-613.
29. Littman AJ, Beresford SA, White E. The association of dietary fat and plant foods with endometrial cancer (United States). Cancer Causes and Control. 2001;12:691-702.
30. McCann SE, Freudenheim JL, Marshall J, Brasure RR, Swanson MK, Graham S. Diet in the epidemiology of endometrial cancer in western New York (United States). Cancer Causes and Control. 2000;11:965-974.
31. Jain MG, Howe GR, Rohan TE. Nutritional factors and endometrial cancer in Ontario, Canada. Cancer Causes and Control. 2000;7:288-296.
32. McCullough ML, Robertson A, Jacobs EJ, Chao A, Calle EE, Thun MJ. A prospective study of diet and stomach cancer mortality in United States men and women. Cancer Epidem, Bio & Prev. 2001;10(11):1201-1205.
33. Centers for Disease Control and Prevention Preventing Heart Disease and Stroke, accessed 01/29/02.
34. American Heart Association Inc. 2001. www.amheart/org. Cardiovascular Disease Statistics, accessed 01/29/02.
35. Fung TT, Willett WC, Stampfer MJ, Manson JE, Hu FB. Dietary patterns and the risk of coronary heart disease in women. Arch Intern Med.2001;161:1857-1862.
36. Joshipura KJ, Hu FB, Manson JE, et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Int Med.2001;134:1106-1114.
37. Liu S, Lee I, Ajani U, Cole S, Buring J, Manson J. Intake of vegetables rich in carotenoids and risk of coronary heart disease in men: the Physician's Health Study. Int J Epidemiol. 2000.
38. Liu S, Manson JE, Lee M-I, et al. Fruit and vegetable intake and risk of cardiovascular disease: The Women's Healthy Study. Am J Clin Nutr.2000;72:922-928.
39. Eichholzer M, Luthy J, Gutzwiller F, Stahelin HB. The role of folate, antioxidant vitamins and other constituents in fruit and vegetables in the prevention of cardiovascular disease: The epidemiological evidence. Int J Vitam Nutr Res. 2001;71(1):5-17.
40. Brouwer IA, van Dusseldorp M, West CE, et al. Dietary folate from vegetables and citrus fruits decreases plasma homocysteine concentrations in humans in a dietary controlled trial. J Nutr. 1999;129:1135-1139.
41. Broekmans WMR, Klopping-Ketelaars WAA, Schuurman CRW, etal. Fruits and vegetables increase plasma carotenoids and vitamins and decrease homocysteine in humans. J Nutr. 2000;130:1578-1583.
42. Rock C, Moskowitz A, Huizar B, et al. High vegetable and fruit diet intervention in pre-menopausal women with cervical intraepithelial neoplasia. JADA. 2001;101:1167-1174.
43. Jenkins DJA, Kendall CWC, Popovich DG, et al. Effect of a very high fiber vegetable, fruit, and nut dish on serum lipids, and colonic function. Metabolism. 2001;50(4):494-503.
44. Obarzanek E, Sacks FM, Vollmer WM, et al. Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial. Am J Clin Nutr. 2001;74:80-89.
45. Appel LJ, Moore TJ, Obarzanek E, et al. A clinical trial of the effects of dietary patterns on blood pressure. N Engl J Med. 1997;136:1117-1124.
46. Cao G, Russell RM, Lischner N, Prior RL. Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women. J Nutr. 1998;128:2383-2390.
47. Pederson CB, Kyle J, Jenkinson AM, Gardner PT, McPhail DB,Duthie GG. Effects of blueberry and cranberry juice consumption on the plasma antioxidant capacity of healthy female volunteers. Eur J Clin Nutrition. 2000;54:405-408.
48. Strain JJ, Elwood PC, Davis A, et al. Frequency of fruit and vegetable consumption and blood antioxidants in the Caerphilly cohort of older men. Eur J Clin Nutr. 2000;54:828-833.
49. Maskarinee G, Chan CLY, Meng L, Franke AA, Cooney RV. Exploring the feasibility and effects of a high-fruit and vegetable diet in healthy women. Cancer Epidem, Bio & Prev. 1999;8:919-924.
50. Bub A, Watzl B, Abrahamse L, et al. Moderate intervention with carotenoid-rich vegetable products reduces lipid per oxidation in men. JNutr. 2000;130:2200-2206.
51. Record IR, Dreosti IE, McInerney. Changes in plasma antioxidant status following consumption of diets high or low in fruit and vegetables or following dietary supplementation with an antioxidant mixture. Brit JNutr. 2001;85:459-464.
52. van den Berg R, van Vliet T, Broekmans WMR, et al. A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers. J Nutr.2001;131:1714-1722.
53. Steinberg D, Lewis A. Oxidative modification of LDL and atherogenesis. Circulation. 1997;95:1062-1071.
54. Chopra M, O'Neill ME, Keogh N, Wortley G, Southon S,Thurnham DI. Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and non-smokers. Clin Chem. 2000;46(11):1818-1829.
55. Southon S. Increased fruit and vegetable consumption with the EU: potential health benefits. Food Res Int. 2000;33:211-217.
56. Arendt BM, Boetzer AM, Lemoch H, et al. Plasma antioxidant capacity of HIV-seropositive and healthy subjects during long-term ingestion of fruit juices or a fruit-vegetable-concentrate containing antioxidant polyphenols. Eur J Clin Nutrition. 2001;55:786-792.
57. Conlin PR, Chow D, Miller ER, et al. The Effect of Dietary Patternson Blood Pressure Control in Hypertensive Patients: Results from the Dietary Approaches to Stop Hypertension (DASH) Trial. Am J Hypertens.2000;13:949-955.
58. Moore TJ, Conlin PR, Ard J, Svetkey LP. DASH (Dietary Approaches to Stop Hypertension) diet is effective treatment for stage 1 isolated systolic hypertension. Hypertension. 2001;38:155-158.
59. Moline J, Bukharovich IF, Wolff MS, Phillips R. Dietary flavonoids and hypertension: is there a link? Med Hypoth. 2000;55(4):306-309.
60. Joshipura KJ, Ascherio A, Manson JE, et al. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA. 1999;282:1233-1239.
61. Centers for Disease Control and Fast Stats, accessed 01/29/02.
62. Tabak C, Smit HA, Rasanen L, et al. Dietary factors and pulmonary function: a cross sectional study in middle aged men from three European countries. Thorax. 1999;54:1021-1026.
63. Smit HA, Grievink L, Tabak C. Dietary influences on chronic obstructive lung disease and asthma: A review of the epidemiological evidence. Proc Nutr Soc. 1999;58(2):309-319.
64. Tabak C, Arts IC, Smit HA, Heederik D, Kromhout D. Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones. Am J Respir Crit Care Med. 2001;164:61-64.
65. Butland BK, Fehily AM, Elwood PC. Diet, lung function, and lung function decline in a cohort of 2512 middle aged men. Thorax.2000;55:102-108.
66. Centers for Disease Control and Prevention. Press Release - Diabetes rates rise another 6 percent in 1999,accessed 01/29/02
67. Ford ES, Mokdad AH. Fruit and vegetable consumption and diabetes mellitus incidence among U.S. adults. Prev Med. 2001;32:33--39.
68. Meyer K, Kushi LH, Jacobs DR, Slavin J, Seller TA, Folsom AR. Carbohydrates, dietary fiber and incident type 2 diabetes in older women. Am J Clin Nutr. 2000;71:921-930.
69. Sargeant LA, Khaw KT, Bingham S, et al. Fruit and vegetable intake and population glycosylated haemoglobin levels: the EPIC-Norfolk study. Eur J Clin Nutrition. 2001;55:342-348.
70. Centers for Disease Control and Prevention. National Center for Health Statistics. Prevalence of Overweight and Obesity Among Adults: United States, 1999, accessed 2/22/02.
71. McCrory MA, Fuss PJ, Saltzman E, Roberts SB. Dietary determinants of energy intake and weight regulation in healthy adults. J Nutr.2000;130:276S-279S.
72. Rolls BJ. The role of energy density in the over consumption of fat. JNutr. 2000;130:268S-271S.
73. Roberts SB, Heyman MB. Dietary composition and obesity: Do we need to look beyond dietary fat? J Nutr. 2000;130:267S.
74. McCrory MA, Hajduk CL, Roberts SB, Mayer J. Food group associations with BMI: Influence of energy reporting accuracy. (abstract) FASEBJ. 2001; 15 (5): A951.
75. Bell EA, Rolls BJ. Energy density of foods affects energy intake across multiple levels of fat content in lean and obese women. Am J ClinNutr. 2001;73:1010-1018.
76. Epstein LH, Gordy CC, Raynor HA, Beddome M, Kilanowski CK,Paluch R. Increasing fruit and vegetable intake and decreasing fat and sugar intake in families at risk for childhood obesity. Obesity Res.2001;9(3):171-178.
77. Burton-Freeman B. Dietary fiber and energy regulation. J Nutr.2000;130:272S-275S.
78. Van Horn L. Fiber, lipids, and coronary heart disease. Circulation.1997;95:2701-2704.
79. Pereira MA, Ludwig DA. Dietary fiber and bodyweight regulation. Ped Clin North Am. 2001;48(4):969-979.
80. Osler M, Heitmann BL, Gerdes LU, Jorgensen LM, Schroll M. Dietary patterns and mortality in Danish men and women: A prospective observational study. Brit J Nutr. 2001;85:219-225.
81. Strandhagen E, Hansson P-O, Bosaeus I, Isaksson B, Eriksson H. High fruit intake may reduce mortality among middle-aged and elderly men. The study of men born in 1913. Eur J Clin Nutrition. 2000;54:337-341.
82. Centers for Disease Control and Prevention. Osteoporosis among estrogen-deficient women -United States, accessed 01/29/02.
83. Muhlbauer RC. Effect of vegetables on bone metabolism. Nature.1999;401:343-344.
84. Barlet J-P. A possible rut(in) the road. J Bone Min Res.2001;16(5):971.
85. Muhlbauer RC. Rutin cannot explain the effect of vegetables on bone metabolism. J Bone Min Res. 2001;16(5):970.
86. Tucker KL, Hannan MT, Honglei C, Cupples LA, Wilson P, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J ClinNutr. 1999;69:727-736.
87. New SA, Robins SP, Campbell MK, et al. Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health. Am J Clin Nutr.2000;71:142-151.
88. Joseph JA, Shukitt-Hale B, Denisova NA, et al. Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J Neuroscience. 1998;18(19):8047-8055.
89. Joseph JA, Denisova NA, Bielinski D, Fisher DR, Shukitt-Hale B. Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention. Mech Age and Devel. 2000;116:141-153.
90. Perrig WJ, Perrig P, Stahelin HB. The relation between antioxidants and memory performance in the old and very old. J Am Geriatr Soc.1997;45:718-724.
91. Perkins AJ, Hendrie HC, Callahan CM, et al. Association of antioxidants with memory in a multiethnic elderly sample using the Third National Health and Nutrition Examination Survey. Am J Epidemiol.1999;150:37-44.
92. Joseph JA, Shukitt-Hale B, Denisova NA, et al. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach or strawberry supplementation. JNeuroscience. 1999;19(18):8114-8121.
93. Kuresh A, Joseph JA. A possible emerging role of phytochemicals in improving age-related neurological dysfunction: a multiplicity of effects. Free Rad Biol & Med. 2001;30(6):583-594.
94. Denisova NA, Bielinski D, Shukitt-Hale B, et al. Membrane and signaling effects in blueberry-supplemented APP/PS-1 mice: Relation to behavior. Society for Neuroscience Abstracts. 2001;27(2):1719.
95. Commenges D, Scotet V, Renaud S, Jacqmin-Gadda H, Barberger-Gateau P, Dartigues J-F. Intake of flavonoids and dementia. Eur JEpidemiol. 2000;16:357-363.
96. Ishige K, Schubert D, Sagara Y. Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Rad Biol & Med.2001;30:433-446.
97. Riviere S, Birlouez-Aragon I, Nourhashemi F, Vellas B. Low plasma vitamin C in Alzheimer patients despite an adequate diet. Int J Geriatric Psych. 1998;13:749-754.
98. La Rue A, Koeler KM, Wayne SJ, Chiulli SJ, Haaland KY, Garry PJ. Nutritional status and cognitive functioning in a normally aging sample: A 6-y assessment. Am J Clin Nutr. 1997;65:20-29.
99. Purba M, Kouris-Blazos A, Wattanapenpaiboon N, et al. Skin wrinkling: Can food make a difference? J Am Coll Nutr. 2001;20(1):71-80.
100. Diverticulitis. A byproduct of our refined eating habits. Mayo Clinic Health Letter. 1998;16:1-3.
101. Roberts PL, Veiidenheimn MC. Diverticular diseases of the colon. In: Bayless TM, ed. Current Therapy in Gastroenterology and Liver Diseases. Vol. 3. Toronto, Canada: Decker; 1990:416-419.
102. Kennedy MV, Zarling EJ. Answers to ten key questions on diverticular disease of the colon. Comp Ther. 1998;24:364-369.
103. Painter MS, Burkitt DP. Diverticular disease of the colon: a 20thcentury problem. Clin Gastroenterol. 1975;4:3-21.
104. Fisher N, Berry CS, Fearn T, Gregory JA, Hardy J. Cereal dietary fiber consumption and diverticular disease: a lifespan study in rats. Am J ClinNutr. 1985;42:788-804.
105. Brodribb AJM, Humphreys DM. Diverticular disease: three studies.1. Relation to other disorders and fiber intake. Brit Med J. 1976;1:424-425.
106. Aldoori WH, Giovannucci E, Rockett HRH, Sampson L, Rimm EB, Willett WC. A prospective study of dietary fiber types and symptomatic diverticular disease in men. J Nutr. 1998;128:714-719.
107. Aldoori WH, Giovannucci E, Rimm EB, Wing AL, Trichopoulos D, Willett WC. A prospective study of diet and the risk of symptomatic diverticular disease in men. Am J Clin Nutr. 1994;60:757-764.
108. Marlett JA. Content and composition of dietary fiber in 117 frequently consumed foods. JADA. 1992;92:175-186.
109. Kjeldsen-Kragh J, Haugen M, Borchgrevink CF, et al. Controlled trial of fasting and one-year vegetarian diet in rheumatoid arthritis. Lancet. 1991;338:889-902.
110. Kjeldsen-Kragh J, Haugen M, Borchgrevink CF, Forre O. Vegetarian diet for patients with rheumatoid arthritis - status: two years after introduction of the diet. Clin Rheumatol. 1994;13:475-482.
111. Nenonen MT, Helve TA, Rauma AL, Hanninen OO. Uncooked, lactobacilli-rich vegan food and rheumatoid arthritis. Brit J Rheumatol.1998;37:274-281.
112. Liebman B. Vitamin and minerals. What to take. Nutrition Action Newsletter. 1998;25(1):3-5.
113. MRC Vitamin Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet.1991;338:131-137.
114. Wesler MM, Shapiro S, Mitchell AA. Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA. 1993;369:1257-1261.
115. Czeizel AE, Dudas I. Prevention of the first occurrence of neural tube defects by periconceptional vitamin supplementation. N Engl J Med.1992;327:1832-1835.
116. Bower C, Stanley FJ. Dietary folate as a risk factor for neural-tube defects: evidence from a case-control study in Western Australia. Med JAust. 1989;150:613-619.
117. Recommendations for use of folic acid to reduce the number of spina bifida cases and other neural tube defects. JAMA. 1993;269:33-37.
118. Firth Y, Murtaugh MA, Tangney CC. Estimation of individual intakes of folate in women of childbearing age with and without simulation of folic acid fortification. JADA. 1998;98:985-988.
119. Klerk M, Jansen MC, Van't Veer P, Kok FJ, eds. Fruits and vegetables in chronic disease prevention. Waginengen, The Netherlands: GrafischBedrijf Ponsen, BV Looijen; 1998.
120. Taylor A, Jacques PF, Epstein EM. Relations among aging, antioxidant status and cataract. Am J Clin Nutr. 1995;62 (suppl):1439S-1447S.
121. Ryan SJ. Congressional Testimony.: Washington, D.C. U.S. Government Printing Office; 1993.
122. Jacques PF, Chylack LT. Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. Am J ClinNutr. 1991;53:352S-355S.
123. Mares-Perlman JA, Brady WE, Klein BEK, et al. Diet and nuclear lens opacities. Am J Epidemiol. 1995;141:322-334.
124. Hankinson SE, Stampfer MJ, Seddon JM, et al. Nutrient intake and cataract extraction in women: a prospective study. Brit Med J.1992;305:335-339.
125. Brown LM, Hankinson SE, Seddon JM, Rimm EB, Willett WC. A prospective study of carotenoid intake and cataracts among US men. Am J Epidemiol. 1998;147:213.


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